CMap Candidate Details
Structure:
| CMap ID: | C01498 |
| Pert ID: | BRD-K71847383 |
| Compound Name: | cytarabine |
| Targets: | POLA1|POLB|POLD1|POLE |
| MoA: | ribonucleotide reductase inhibitor |
| SMILES: | Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 115968 | BRD-K71847383 | A375 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 116006 | BRD-K71847383 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 116045 | BRD-K71847383 | HA1E | 10 uM | 24 h | -0.31 | -1.27 | 0.74 | 0.0 | 0.0 | 0.0 |
| 116087 | BRD-K71847383 | HCC515 | 10 uM | 24 h | 0.21 | 0.86 | 0.01 | 0.0 | 0.0 | 0.0 |
| 116130 | BRD-K71847383 | HEPG2 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.84 | 0.13 |
| 116178 | BRD-K71847383 | HT29 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 116217 | BRD-K71847383 | MCF??7.00 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.83 | 0.17 |
| 116257 | BRD-K71847383 | PC3 | 1.11 uM | 24 h | 0.17 | 0.7 | 0.0 | 0.0 | 0.0 | 0.0 |