CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01500
Pert ID:	BRD-K47000838
Compound Name:	cytochalasin-b
Targets:	ACTB
MoA:	microtubule inhibitor
SMILES:	C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@]22OC(=O)\C=C/[C@H](O)CCC[C@@H](C)C\C=C\[C@H]2[C@H](O)C1=C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125592	BRD-K47000838	A375	4 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125620	BRD-K47000838	A549	4 uM	24 h	0.0	0.0	0.0	0.24	0.83	0.12
125699	BRD-K47000838	HT29	4 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125745	BRD-K47000838	HUVEC	4 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125806	BRD-K47000838	MCF10A	4 uM	24 h	0.29	1.19	0.42	0.25	0.87	0.17
125831	BRD-K47000838	MCF??7.00	4 uM	24 h	0.25	1.04	0.16	0.0	0.0	0.0
125878	BRD-K47000838	PC3	4 uM	24 h	0.23	0.96	0.07	0.0	0.0	0.0
125898	BRD-K47000838	THP1	0.02 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125943	BRD-K47000838	YAPC	4 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133707	BRD-K47000838	HA1E	1.11 uM	24 h	0.0	0.0	0.0	-0.29	-0.99	0.5
133737	BRD-K47000838	HEK293	1.11 uM	24 h	0.24	1.02	0.13	-0.25	-0.85	0.19
133775	BRD-K47000838	HELA	1.11 uM	24 h	0.0	0.0	0.0	0.25	0.9	0.21
133830	BRD-K47000838	JURKAT	0.04 uM	24 h	-0.22	-0.9	0.04	0.33	1.16	0.9
133921	BRD-K47000838	MDAMB231	1.11 uM	24 h	0.0	0.0	0.0	-0.4	-1.33	1.78

Summary