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CMap Candidate Details

Structure:
CMap ID: C01502
Pert ID: BRD-K87737963
Compound Name: cyt387
Targets: JAK1|JAK2|JAK3
MoA:
SMILES: O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
92008 BRD-K87737963 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92050 BRD-K87737963 BT20 10 uM 3 h 0.0 0.0 0.0 -0.28 -0.93 0.35
92119 BRD-K87737963 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92151 BRD-K87737963 HS578T 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92245 BRD-K87737963 MCF10A 3.33 uM 3 h 0.16 0.68 0.0 0.0 0.0 0.0
92265 BRD-K87737963 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92324 BRD-K87737963 MDAMB231 0.12 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92381 BRD-K87737963 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95814 BRD-K87737963 NPC 1.11 uM 6 h 0.0 0.0 0.0 0.4 1.4 2.18
118073 BRD-K87737963 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118116 BRD-K87737963 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118207 BRD-K87737963 HEPG2 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
127840 BRD-K87737963 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.22
127893 BRD-K87737963 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127914 BRD-K87737963 HUVEC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128037 BRD-K87737963 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
128063 BRD-K87737963 YAPC 3.33 uM 24 h 0.27 1.14 0.31 -0.31 -1.04 0.66
135541 BRD-K87737963 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135633 BRD-K87737963 JURKAT 2.22 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).