CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01515
Pert ID:	BRD-K71822263
Compound Name:	D-Serine
Targets:	GLRA1\|GRIN1\|GRIN2A\|GRIN2B\|GRIN2C\|GRIN2D\|SERPINB3
MoA:	glutamate receptor agonist
SMILES:	N[C@H](CO)C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
126853	BRD-K71822263	MCF??7.00	10 uM	24 h	0.24	1.01	0.12	0.0	0.0	0.0
126897	BRD-K71822263	MDAMB231	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126965	BRD-K71822263	THP1	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127002	BRD-K71822263	YAPC	0.125 uM	24 h	-0.25	-1.02	0.19	0.0	0.0	0.0
134683	BRD-K71822263	A375	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134708	BRD-K71822263	A549	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134739	BRD-K71822263	HA1E	0.08 uM	24 h	-0.22	-0.9	0.05	-0.28	-0.95	0.42
134774	BRD-K71822263	HEK293	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134803	BRD-K71822263	HELA	0.08 uM	24 h	0.0	0.0	0.0	0.31	1.08	0.67
134833	BRD-K71822263	HT29	0.74 uM	24 h	-0.19	-0.78	0.0	0.27	0.95	0.32
134879	BRD-K71822263	HUVEC	0.25 uM	24 h	0.22	0.91	0.03	0.27	0.97	0.35
134905	BRD-K71822263	JURKAT	0.08 uM	24 h	0.27	1.11	0.26	0.0	0.0	0.0
134933	BRD-K71822263	MCF10A	2.22 uM	24 h	0.0	0.0	0.0	-0.34	-1.16	1.1
134969	BRD-K71822263	PC3	2.22 uM	24 h	-0.28	-1.16	0.48	0.0	0.0	0.0

Summary