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CMap Candidate Details

Structure:
CMap ID: C01517
Pert ID: BRD-K26997899
Compound Name: D-64131
Targets: TUBB
MoA: microtubule inhibitor
SMILES: COc1ccc2[nH]c(cc2c1)C(=O)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3003 BRD-K26997899 HA1E 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.52
3169 BRD-K26997899 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3762 BRD-K26997899 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44555 BRD-K26997899 A549 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.39
44911 BRD-K26997899 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45215 BRD-K26997899 HEPG2 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
45481 BRD-K26997899 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45674 BRD-K26997899 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46030 BRD-K26997899 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46664 BRD-K26997899 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53504 BRD-K26997899 HUH7 10 uM 24 h -0.22 -0.9 0.04 -0.49 -1.65 15.65
53651 BRD-K26997899 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96637 BRD-K26997899 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.44 -1.47 15.35
96703 BRD-K26997899 PC3 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
97710 BRD-K26997899 NKDBA 3.33 uM 24 h -0.22 -0.91 0.05 -0.3 -1.0 0.54
99786 BRD-K26997899 U2OS 10 uM 6 h 0.27 1.13 0.28 -0.28 -0.96 0.43
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).