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CMap Candidate Details

Structure:
CMap ID: C01523
Pert ID: BRD-K35520305
Compound Name: dacarbazine
Targets: PGD|POLA2
MoA: DNA alkylating agent
SMILES: CN(C)\N=N\c1[nH]cnc1C(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91209 BRD-K35520305 HUH7 20 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
115711 BRD-K35520305 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
115752 BRD-K35520305 HCC515 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115795 BRD-K35520305 HEPG2 1.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115841 BRD-K35520305 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120533 BRD-K35520305 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120575 BRD-K35520305 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120733 BRD-K35520305 JURKAT 10 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
120760 BRD-K35520305 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120841 BRD-K35520305 YAPC 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.24
129042 BRD-K35520305 HELA 0.25 uM 3 h -0.19 -0.8 0.0 0.32 1.14 0.86
129085 BRD-K35520305 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).