CMap Candidate Details
Structure:
| CMap ID: | C01552 |
| Pert ID: | BRD-K19085898 |
| Compound Name: | darapladib |
| Targets: | PLA2G7 |
| MoA: | phospholipase inhibitor |
| SMILES: | CCN(CC)CCN(Cc1ccc(cc1)-c1ccc(cc1)C(F)(F)F)C(=O)Cn1c2CCCc2c(=O)nc1SCc1ccc(F)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121433 | BRD-K19085898 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.93 |
| 121474 | BRD-K19085898 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121497 | BRD-K19085898 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129395 | BRD-K19085898 | A375 | 2.22 uM | 24 h | 0.33 | 1.38 | 0.97 | 0.27 | 0.96 | 0.33 |
| 129426 | BRD-K19085898 | HA1E | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129460 | BRD-K19085898 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129511 | BRD-K19085898 | MCF??7.00 | 0.74 uM | 24 h | -0.2 | -0.82 | 0.0 | -0.44 | -1.49 | 15.35 |