CMap Candidate Details
Structure:
| CMap ID: | C01554 |
| Pert ID: | BRD-K95773607 |
| Compound Name: | darifenacin |
| Targets: | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 |
| MoA: | acetylcholine receptor antagonist |
| SMILES: | NC(=O)C([C@@H]1CCN(CCc2ccc3OCCc3c2)C1)(c1ccccc1)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96626 | BRD-K95773607 | A375 | 10 uM | 24 h | 0.19 | 0.81 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96694 | BRD-K95773607 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128134 | BRD-K95773607 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128166 | BRD-K95773607 | HEK293 | 10 uM | 24 h | 0.21 | 0.87 | 0.01 | 0.0 | 0.0 | 0.0 |
| 128184 | BRD-K95773607 | HT29 | 10 uM | 24 h | -0.28 | -1.15 | 0.44 | -0.31 | -1.04 | 0.68 |
| 128215 | BRD-K95773607 | MCF10A | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.01 | 0.57 |
| 128257 | BRD-K95773607 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128294 | BRD-K95773607 | MDAMB231 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.97 | 0.46 |
| 135804 | BRD-K95773607 | HA1E | 0.74 uM | 24 h | -0.24 | -0.99 | 0.14 | 0.0 | 0.0 | 0.0 |
| 135889 | BRD-K95773607 | HELA | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135978 | BRD-K95773607 | JURKAT | 2.22 uM | 24 h | -0.18 | -0.75 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136085 | BRD-K95773607 | THP1 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136124 | BRD-K95773607 | YAPC | 0.01 uM | 24 h | -0.24 | -1.0 | 0.14 | 0.0 | 0.0 | 0.0 |