CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01561
Pert ID:	BRD-K43389675
Compound Name:	daunorubicin
Targets:	TOP2A\|TOP2B
MoA:	RNA synthesis inhibitor; topoisomerase inhibitor
SMILES:	COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
989	BRD-K43389675	CD34	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
1045	BRD-K43389675	HL60	1.11 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
1109	BRD-K43389675	U937	0.37 uM	6 h	0.0	0.0	0.0	-0.37	-1.25	1.35
41937	BRD-K43389675	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42366	BRD-K43389675	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42690	BRD-K43389675	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43192	BRD-K43389675	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
43854	BRD-K43389675	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44120	BRD-K43389675	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99539	BRD-K43389675	U2OS	3.33 uM	6 h	-0.28	-1.15	0.44	0.31	1.09	0.67
115954	BRD-K43389675	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
116031	BRD-K43389675	HA1E	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
116073	BRD-K43389675	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
116162	BRD-K43389675	HT29	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
116242	BRD-K43389675	PC3	0.04 uM	24 h	0.26	1.07	0.19	0.0	0.0	0.0

Summary