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CMap Candidate Details

Structure:
CMap ID: C01578
Pert ID: BRD-K97010173
Compound Name: deferasirox
Targets: CYP3A4
MoA: chelating agent
SMILES: OC(=O)c1ccc(cc1)-n1nc(nc1-c1ccccc1O)-c1ccccc1O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128396 BRD-K97010173 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128456 BRD-K97010173 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
128485 BRD-K97010173 HELA 10 uM 24 h 0.24 1.02 0.12 -0.21 -0.7 0.03
128566 BRD-K97010173 JURKAT 10 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
128603 BRD-K97010173 MCF10A 10 uM 24 h -0.31 -1.3 0.81 0.0 0.0 0.0
128612 BRD-K97010173 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128658 BRD-K97010173 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128738 BRD-K97010173 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128778 BRD-K97010173 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
136195 BRD-K97010173 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136240 BRD-K97010173 HA1E 2.22 uM 24 h -0.29 -1.22 0.61 0.0 0.0 0.0
136298 BRD-K97010173 HT29 0.08 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
136372 BRD-K97010173 PC3 2.22 uM 24 h 0.27 1.14 0.31 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).