CMap Candidate Details
Structure:
| CMap ID: | C01591 |
| Pert ID: | BRD-K59325863 |
| Compound Name: | delanzomib |
| Targets: | CMA1|CTSG|CYP3A4|ELANE |
| MoA: | proteasome inhibitor |
| SMILES: | CC(C)C[C@H](NC(=O)[C@@H](NC(=O)c1cccc(n1)-c1ccccc1)[C@@H](C)O)B(O)O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95307 | BRD-K59325863 | A549 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95432 | BRD-K59325863 | U2OS | 0.08 uM | 48 h | 0.24 | 0.99 | 0.09 | 0.0 | 0.0 | 0.0 |
| 96417 | BRD-K59325863 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123587 | BRD-K59325863 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123702 | BRD-K59325863 | MCF10A | 3.33 uM | 24 h | 0.21 | 0.88 | 0.02 | 0.0 | 0.0 | 0.0 |
| 123729 | BRD-K59325863 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123772 | BRD-K59325863 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131991 | BRD-K59325863 | A375 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132019 | BRD-K59325863 | HA1E | 0.01 uM | 24 h | 0.25 | 1.06 | 0.19 | 0.0 | 0.0 | 0.0 |
| 132044 | BRD-K59325863 | HELA | 0.01 uM | 24 h | 0.24 | 1.0 | 0.11 | 0.0 | 0.0 | 0.0 |
| 132062 | BRD-K59325863 | HT29 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.09 | 0.82 |