CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01614
Pert ID:	BRD-A49399758
Compound Name:	desmopressin-acetate
Targets:	AVPR1A\|AVPR1B\|AVPR2\|OXTR
MoA:	vasopressin receptor agonist
SMILES:	NC(=O)CCC1NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2ccc(O)cc2)NC(=O)CCSSCC(NC(=O)C(CC(N)=O)NC1=O)C(=O)N1CCCC1C(=O)NC(CCCNC(N)=N)C(=O)NCC(N)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125264	BRD-A49399758	A549	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125328	BRD-A49399758	HEK293	10 uM	24 h	0.0	0.0	0.0	-0.22	-0.72	0.04
125420	BRD-A49399758	MCF10A	3.33 uM	24 h	-0.21	-0.89	0.04	-0.26	-0.88	0.24
125455	BRD-A49399758	MCF??7.00	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125499	BRD-A49399758	PC3	0.37 uM	24 h	0.0	0.0	0.0	-0.3	-1.01	0.57
125528	BRD-A49399758	THP1	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133347	BRD-A49399758	A375	0.01 uM	24 h	0.0	0.0	0.0	-0.3	-1.01	0.57
133396	BRD-A49399758	HA1E	0.74 uM	24 h	0.0	0.0	0.0	0.26	0.91	0.23
133431	BRD-A49399758	HELA	0.01 uM	24 h	-0.29	-1.2	0.55	0.0	0.0	0.0
133461	BRD-A49399758	HT29	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133488	BRD-A49399758	JURKAT	0.01 uM	24 h	-0.22	-0.93	0.07	0.22	0.77	0.06
133563	BRD-A49399758	MDAMB231	0.74 uM	24 h	0.23	0.97	0.08	-0.34	-1.13	0.98
133641	BRD-A49399758	YAPC	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary