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CMap Candidate Details

Structure:
CMap ID: C01617
Pert ID: BRD-A49447682
Compound Name: desoximetasone
Targets: NR3C1|PLA2G1B
MoA: glucocorticoid receptor agonist
SMILES: C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5266 BRD-A49447682 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5524 BRD-A49447682 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5843 BRD-A49447682 HEPG2 10 uM 6 h -0.24 -1.01 0.16 0.24 0.86 0.15
6136 BRD-A49447682 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6468 BRD-A49447682 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37083 BRD-A49447682 A375 10 uM 6 h 0.27 1.12 0.26 -0.33 -1.09 0.85
37345 BRD-A49447682 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37511 BRD-A49447682 ASC 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
38021 BRD-A49447682 HT29 10 uM 6 h 0.0 0.0 0.0 0.35 1.25 1.29
38154 BRD-A49447682 MCF??7.00 10 uM 24 h -0.27 -1.12 0.39 0.31 1.11 0.72
38360 BRD-A49447682 NPC 10 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.59
38867 BRD-A49447682 SKB 10 uM 24 h 0.18 0.74 0.0 -0.21 -0.71 0.04
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).