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CMap Candidate Details

Structure:
CMap ID: C01619
Pert ID: BRD-K98521173
Compound Name: desoxycortone
Targets: NR3C1|NR3C2
MoA: mineralocorticoid receptor agonist
SMILES: C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3082 BRD-K98521173 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3420 BRD-K98521173 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3658 BRD-K98521173 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3916 BRD-K98521173 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39256 BRD-K98521173 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39541 BRD-K98521173 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39872 BRD-K98521173 ASC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
40158 BRD-K98521173 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.24
40415 BRD-K98521173 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40675 BRD-K98521173 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40966 BRD-K98521173 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41290 BRD-K98521173 NPC 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
41635 BRD-K98521173 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).