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CMap Candidate Details

Structure:
CMap ID: C01621
Pert ID: BRD-A98845662
Compound Name: desvenlafaxine
Targets: SLC6A2|SLC6A3|SLC6A4
MoA: serotonin norepinephrine reuptake inhibitor (SNRI)
SMILES: CN(C)CC(c1ccc(O)cc1)C1(O)CCCCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127753 BRD-A98845662 A375 0.04 uM 24 h 0.24 1.0 0.11 0.25 0.87 0.18
127798 BRD-A98845662 A549 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.43
127831 BRD-A98845662 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127881 BRD-A98845662 HEK293 1.11 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
127955 BRD-A98845662 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128006 BRD-A98845662 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
128032 BRD-A98845662 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128088 BRD-A98845662 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135582 BRD-A98845662 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135623 BRD-A98845662 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135673 BRD-A98845662 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135727 BRD-A98845662 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).