CMap Candidate Details
Structure:
| CMap ID: | C01630 |
| Pert ID: | BRD-K07609981 |
| Compound Name: | dexloxiglumide |
| Targets: | CCKAR |
| MoA: | CCK receptor antagonist |
| SMILES: | CCCCCN(CCCOC)C(=O)[C@@H](CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122558 | BRD-K07609981 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122610 | BRD-K07609981 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.87 | 0.17 |
| 122646 | BRD-K07609981 | HEK293 | 1.11 uM | 24 h | 0.33 | 1.37 | 0.97 | 0.25 | 0.88 | 0.18 |
| 122741 | BRD-K07609981 | MCF10A | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122779 | BRD-K07609981 | MDAMB231 | 1.11 uM | 24 h | 0.24 | 1.01 | 0.11 | 0.3 | 1.05 | 0.57 |
| 122803 | BRD-K07609981 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122824 | BRD-K07609981 | YAPC | 10 uM | 24 h | -0.21 | -0.86 | 0.02 | -0.23 | -0.79 | 0.1 |
| 130892 | BRD-K07609981 | A549 | 0.25 uM | 24 h | 0.28 | 1.16 | 0.34 | 0.0 | 0.0 | 0.0 |
| 130981 | BRD-K07609981 | HELA | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131009 | BRD-K07609981 | HT29 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.38 | 1.34 | 1.72 |
| 131063 | BRD-K07609981 | HUVEC | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131096 | BRD-K07609981 | MCF??7.00 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |