CMap Candidate Details
Structure:
CMap ID: | C01634 |
Pert ID: | BRD-K07265709 |
Compound Name: | dexrazoxane |
Targets: | TOP2A|TOP2B |
MoA: | chelating agent; topoisomerase inhibitor |
SMILES: | C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1 |
InchiKey: | |
Compound Aliases: |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
33771 | BRD-K07265709 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.78 | 0.1 |
34036 | BRD-K07265709 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
34308 | BRD-K07265709 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
34550 | BRD-K07265709 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
34819 | BRD-K07265709 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.19 | 0.67 | 0.01 |
35086 | BRD-K07265709 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
35293 | BRD-K07265709 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.83 | 0.12 |
35535 | BRD-K07265709 | NEU | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.79 | 0.11 |
35721 | BRD-K07265709 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.04 | 0.66 |
35927 | BRD-K07265709 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
36194 | BRD-K07265709 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.91 |
36487 | BRD-K07265709 | SKB | 10 uM | 24 h | -0.28 | -1.15 | 0.44 | -0.38 | -1.29 | 1.53 |
36769 | BRD-K07265709 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.38 |