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CMap Candidate Details

Structure:
CMap ID: C00164
Pert ID: BRD-K96029467
Compound Name: alagebrium
Targets:
MoA: glycosylation inhibitor
SMILES: Cc1sc[n+](CC(=O)c2ccccc2)c1C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121722 BRD-K96029467 A375 3.33 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
129796 BRD-K96029467 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.81
129835 BRD-K96029467 HEK293 0.25 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
129874 BRD-K96029467 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129898 BRD-K96029467 HT29 0.08 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
129961 BRD-K96029467 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130004 BRD-K96029467 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.61
130046 BRD-K96029467 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130085 BRD-K96029467 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130117 BRD-K96029467 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130163 BRD-K96029467 YAPC 0.25 uM 24 h 0.24 1.02 0.12 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).