Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C01641
Pert ID: BRD-K06014311
Compound Name: DH-97
Targets: MTNR1B
MoA: melatonin receptor antagonist
SMILES: CCCCC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4187 BRD-K06014311 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.06 0.73
4345 BRD-K06014311 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4639 BRD-K06014311 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5024 BRD-K06014311 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
44285 BRD-K06014311 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44512 BRD-K06014311 A549 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
44828 BRD-K06014311 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45140 BRD-K06014311 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45408 BRD-K06014311 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45639 BRD-K06014311 MCF??7.00 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
45943 BRD-K06014311 NPC 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.51
46263 BRD-K06014311 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46579 BRD-K06014311 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100004 BRD-K06014311 U2OS 10 uM 6 h 0.18 0.77 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).