CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01643
Pert ID:	BRD-K69122748
Compound Name:	diacerein
Targets:	IL1B
MoA:	interleukin inhibitor
SMILES:	CC(=O)Oc1cccc2C(=O)c3cc(cc(OC(C)=O)c3C(=O)c12)C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
52188	BRD-K69122748	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	-0.38	-1.27	1.4
52323	BRD-K69122748	PC3	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.04	0.67
126770	BRD-K69122748	JURKAT	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126880	BRD-K69122748	MDAMB231	10 uM	24 h	-0.25	-1.02	0.18	0.32	1.14	0.87
126942	BRD-K69122748	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126988	BRD-K69122748	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134672	BRD-K69122748	A375	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134696	BRD-K69122748	A549	0.01 uM	24 h	0.0	0.0	0.0	0.22	0.79	0.07
134724	BRD-K69122748	HA1E	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134761	BRD-K69122748	HEK293	0.01 uM	24 h	0.0	0.0	0.0	-0.44	-1.47	15.35
134793	BRD-K69122748	HELA	2.22 uM	24 h	0.0	0.0	0.0	-0.38	-1.29	1.52
134821	BRD-K69122748	HT29	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134857	BRD-K69122748	HUVEC	0.01 uM	24 h	0.23	0.98	0.09	-0.27	-0.9	0.29
134921	BRD-K69122748	MCF10A	2.22 uM	24 h	0.0	0.0	0.0	0.25	0.89	0.2

Summary