CMap Candidate Details
Structure:
| CMap ID: | C01650 |
| Pert ID: | BRD-K16508793 |
| Compound Name: | diazepam |
| Targets: | ADRA1A|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GABRR1|GABRR2|GABRR3|TSPO |
| MoA: | benzodiazepine receptor agonist |
| SMILES: | CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 2091 | BRD-K16508793 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.68 | 0.02 |
| 2619 | BRD-K16508793 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 97119 | BRD-K16508793 | A375 | 10 uM | 24 h | -0.25 | -1.02 | 0.19 | -0.24 | -0.81 | 0.13 |
| 97184 | BRD-K16508793 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.83 | 0.16 |
| 100147 | BRD-K16508793 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120272 | BRD-K16508793 | A549 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120310 | BRD-K16508793 | HA1E | 3.33 uM | 24 h | 0.23 | 0.95 | 0.06 | 0.24 | 0.87 | 0.17 |
| 120338 | BRD-K16508793 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120401 | BRD-K16508793 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120467 | BRD-K16508793 | YAPC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128944 | BRD-K16508793 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |