CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01662
Pert ID:	BRD-K08252256
Compound Name:	diclofenac
Targets:	AKR1C3\|ALOX5\|ASIC1\|ASIC3\|KCNQ2\|KCNQ3\|PLA2G2A\|PPARG\|PTGS1\|PTGS2\|SCN4A
MoA:	cyclooxygenase inhibitor
SMILES:	OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5575	BRD-K08252256	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
6519	BRD-K08252256	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42052	BRD-K08252256	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42282	BRD-K08252256	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42616	BRD-K08252256	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42919	BRD-K08252256	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43780	BRD-K08252256	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44061	BRD-K08252256	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91239	BRD-K08252256	HUH7	12 uM	72 h	0.22	0.92	0.04	-0.25	-0.86	0.21
98866	BRD-K08252256	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99217	BRD-K08252256	NPC	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
100031	BRD-K08252256	U2OS	10 uM	6 h	0.0	0.0	0.0	-0.27	-0.92	0.34
121214	BRD-K08252256	HA1E	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121304	BRD-K08252256	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129242	BRD-K08252256	A375	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129270	BRD-K08252256	HELA	0.25 uM	3 h	0.0	0.0	0.0	0.0	0.0	0.0
129325	BRD-K08252256	MCF??7.00	0.01 uM	24 h	-0.23	-0.94	0.08	0.0	0.0	0.0
129362	BRD-K08252256	YAPC	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary