CMap Candidate Details
Structure:
| CMap ID: | C01726 |
| Pert ID: | BRD-K94436377 |
| Compound Name: | diosmin |
| Targets: | AHR |
| MoA: | aryl hydrocarbon receptor agonist; capillary stabilizing agent |
| SMILES: | COc1ccc(cc1O)-c1cc(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2o1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 128211 | BRD-K94436377 | MCF10A | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128290 | BRD-K94436377 | MDAMB231 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.37 |
| 135755 | BRD-K94436377 | A375 | 0.74 uM | 24 h | -0.2 | -0.84 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135773 | BRD-K94436377 | A549 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.23 | 1.25 |
| 135800 | BRD-K94436377 | HA1E | 0.01 uM | 24 h | -0.29 | -1.2 | 0.56 | -0.32 | -1.07 | 0.75 |
| 135844 | BRD-K94436377 | HEK293 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135885 | BRD-K94436377 | HELA | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135933 | BRD-K94436377 | HT29 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135974 | BRD-K94436377 | JURKAT | 0.74 uM | 24 h | 0.3 | 1.23 | 0.5 | -0.36 | -1.22 | 1.24 |
| 136022 | BRD-K94436377 | MCF??7.00 | 0.03 uM | 24 h | -0.22 | -0.91 | 0.05 | 0.0 | 0.0 | 0.0 |
| 136051 | BRD-K94436377 | PC3 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.09 | 0.67 |
| 136082 | BRD-K94436377 | THP1 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136120 | BRD-K94436377 | YAPC | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |