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CMap Candidate Details

Structure:
CMap ID: C01732
Pert ID: BRD-K47278471
Compound Name: diphenhydramine
Targets: HRH1
MoA: histamine receptor antagonist
SMILES: CN(C)CCOC(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24444 BRD-K47278471 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24673 BRD-K47278471 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24780 BRD-K47278471 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24912 BRD-K47278471 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25164 BRD-K47278471 PC3 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
25375 BRD-K47278471 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51350 BRD-K47278471 MCF??7.00 10 uM 6 h 0.25 1.04 0.15 0.0 0.0 0.0
52917 BRD-K47278471 HEPG2 40 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
90976 BRD-K47278471 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).