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CMap Candidate Details

Structure:
CMap ID: C01733
Pert ID: BRD-K01663662
Compound Name: diphenidol
Targets: CHRM1|CHRM2|CHRM3|CHRM4
MoA: acetylcholine receptor agonist
SMILES: OC(CCCN1CCCCC1)(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4336 BRD-K01663662 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5019 BRD-K01663662 VCAP 10 uM 6 h 0.18 0.75 0.0 0.0 0.0 0.0
44814 BRD-K01663662 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
45130 BRD-K01663662 HEPG2 10 uM 6 h 0.22 0.93 0.05 0.0 0.0 0.0
45931 BRD-K01663662 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46249 BRD-K01663662 PHH 10 uM 24 h -0.31 -1.29 0.77 0.0 0.0 0.0
46564 BRD-K01663662 SKB 10 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
122860 BRD-K01663662 HA1E 0.125 uM 24 h -0.25 -1.06 0.24 0.0 0.0 0.0
122895 BRD-K01663662 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122940 BRD-K01663662 HELA 0.125 uM 24 h 0.3 1.23 0.5 0.0 0.0 0.0
123020 BRD-K01663662 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123109 BRD-K01663662 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
123181 BRD-K01663662 THP1 0.125 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
123216 BRD-K01663662 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131208 BRD-K01663662 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131244 BRD-K01663662 A549 0.01 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
131326 BRD-K01663662 HT29 0.74 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
131357 BRD-K01663662 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
131397 BRD-K01663662 MCF10A 0.03 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
131436 BRD-K01663662 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
131463 BRD-K01663662 PC3 0.08 uM 24 h -0.34 -1.41 1.42 0.29 1.01 0.45
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).