CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01764
Pert ID:	BRD-A78322124
Compound Name:	dobutamine
Targets:	ADRB1\|ADRB2
MoA:	adrenergic receptor agonist
SMILES:	CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2973	BRD-A78322124	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
3118	BRD-A78322124	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3702	BRD-A78322124	VCAP	10 uM	24 h	-0.18	-0.75	0.0	-0.28	-0.93	0.34
44260	BRD-A78322124	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44651	BRD-A78322124	A549	10 uM	6 h	-0.35	-1.46	1.43	0.0	0.0	0.0
44786	BRD-A78322124	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45106	BRD-A78322124	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45377	BRD-A78322124	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45906	BRD-A78322124	NPC	10 uM	24 h	-0.23	-0.94	0.08	-0.23	-0.78	0.09
46222	BRD-A78322124	PHH	10 uM	24 h	0.25	1.03	0.14	-0.27	-0.92	0.31
46537	BRD-A78322124	SKB	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.97	0.45
51312	BRD-A78322124	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.35	1.25	1.29
51411	BRD-A78322124	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91085	BRD-A78322124	HUH7	12 uM	72 h	0.0	0.0	0.0	-0.25	-0.83	0.17

Summary