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CMap Candidate Details

Structure:
CMap ID: C01795
Pert ID: BRD-K92093830
Compound Name: doxorubicin
Targets: TOP2A
MoA: topoisomerase inhibitor
SMILES: COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4259 BRD-K92093830 HA1E 10 uM 6 h 0.0 0.0 0.0 0.19 0.67 0.01
4827 BRD-K92093830 PC3 10 uM 6 h 0.0 0.0 0.0 0.36 1.29 1.49
25543 BRD-K92093830 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37198 BRD-K92093830 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37760 BRD-K92093830 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37957 BRD-K92093830 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39021 BRD-K92093830 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51646 BRD-K92093830 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90558 BRD-K92093830 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90874 BRD-K92093830 MCF10A 1.11 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
117144 BRD-K92093830 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127876 BRD-K92093830 HEK293 0.37 uM 24 h 0.2 0.84 0.0 -0.32 -1.07 0.75
127950 BRD-K92093830 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128084 BRD-K92093830 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
135577 BRD-K92093830 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135619 BRD-K92093830 HT29 0.01 uM 24 h -0.3 -1.24 0.65 0.0 0.0 0.0
135668 BRD-K92093830 JURKAT 0.25 uM 24 h 0.28 1.16 0.35 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).