CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01800
Pert ID:	BRD-K01824921
Compound Name:	DPCPX
Targets:	ADORA1\|ADORA2A\|ADORA2B\|ADORA3
MoA:	adenosine receptor antagonist
SMILES:	CCCn1c2[nH]c(nc2c(=O)n(CCC)c1=O)C1CCCC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
96484	BRD-K01824921	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99964	BRD-K01824921	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
122847	BRD-K01824921	A549	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122898	BRD-K01824921	HEK293	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122974	BRD-K01824921	HT29	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123023	BRD-K01824921	JURKAT	10 uM	24 h	0.0	0.0	0.0	-0.22	-0.73	0.05
123112	BRD-K01824921	MDAMB231	10 uM	24 h	0.34	1.41	1.03	0.24	0.84	0.13
123184	BRD-K01824921	THP1	1.11 uM	24 h	0.0	0.0	0.0	-0.24	-0.81	0.12
131281	BRD-K01824921	HA1E	0.74 uM	24 h	0.25	1.02	0.13	0.0	0.0	0.0
131307	BRD-K01824921	HELA	0.03 uM	24 h	0.0	0.0	0.0	0.38	1.33	1.72
131360	BRD-K01824921	HUVEC	0.08 uM	24 h	0.29	1.22	0.48	0.34	1.19	1.02
131400	BRD-K01824921	MCF10A	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131438	BRD-K01824921	MCF??7.00	0.01 uM	24 h	-0.24	-0.98	0.12	-0.29	-0.99	0.5
131465	BRD-K01824921	PC3	0.25 uM	24 h	0.0	0.0	0.0	0.23	0.83	0.12
131498	BRD-K01824921	YAPC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary