CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01827
Pert ID:	BRD-K68620903
Compound Name:	dydrogesterone
Targets:	PGR
MoA:	progesterone receptor agonist
SMILES:	CC(=O)[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)CC[C@@]4(C)[C@@H]3CC[C@]12C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1609	BRD-K68620903	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
2115	BRD-K68620903	HCC515	10 uM	6 h	0.0	0.0	0.0	0.24	0.86	0.15
2413	BRD-K68620903	PC3	10 uM	6 h	0.0	0.0	0.0	-0.21	-0.69	0.03
2583	BRD-K68620903	VCAP	10 uM	24 h	0.18	0.76	0.0	0.0	0.0	0.0
41831	BRD-K68620903	A375	10 uM	6 h	0.0	0.0	0.0	-0.26	-0.87	0.24
42135	BRD-K68620903	A549	10 uM	6 h	0.17	0.72	0.0	-0.25	-0.85	0.19
42451	BRD-K68620903	ASC	10 uM	24 h	-0.22	-0.91	0.05	-0.24	-0.82	0.15
42763	BRD-K68620903	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43062	BRD-K68620903	HT29	10 uM	6 h	0.0	0.0	0.0	-0.15	-0.5	0.0
43348	BRD-K68620903	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43629	BRD-K68620903	NPC	10 uM	24 h	-0.25	-1.05	0.24	-0.26	-0.88	0.26
43929	BRD-K68620903	PHH	10 uM	24 h	0.19	0.79	0.0	0.26	0.94	0.28
44186	BRD-K68620903	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99392	BRD-K68620903	U2OS	6.66 uM	6 h	0.0	0.0	0.0	-0.28	-0.95	0.39

Summary