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CMap Candidate Details

Structure:
CMap ID: C01839
Pert ID: BRD-A96485169
Compound Name: EBPC
Targets: AKR1B1
MoA: aldose reductase inhibitor
SMILES: CCOC(=O)C1CN(Cc2ccccc2)C(=O)C1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1525 BRD-A96485169 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2064 BRD-A96485169 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2286 BRD-A96485169 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2621 BRD-A96485169 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41695 BRD-A96485169 A375 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.68 0.02
41893 BRD-A96485169 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42249 BRD-A96485169 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42586 BRD-A96485169 HEPG2 10 uM 6 h -0.25 -1.04 0.21 0.0 0.0 0.0
42891 BRD-A96485169 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43139 BRD-A96485169 MCF??7.00 10 uM 24 h -0.24 -0.98 0.12 -0.27 -0.9 0.28
43446 BRD-A96485169 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43753 BRD-A96485169 PHH 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
44038 BRD-A96485169 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100419 BRD-A96485169 U2OS 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.59
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).