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CMap Candidate Details

Structure:
CMap ID: C00184
Pert ID: BRD-A09056319
Compound Name: alfuzosin
Targets: ADRA1A|ADRA1B|ADRA1D|KCNH2
MoA: adrenergic receptor antagonist
SMILES: COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C1CCCO1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5249 BRD-A09056319 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5710 BRD-A09056319 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5820 BRD-A09056319 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6232 BRD-A09056319 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24979 BRD-A09056319 MCF??7.00 10 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
25465 BRD-A09056319 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37040 BRD-A09056319 A375 10 uM 6 h 0.0 0.0 0.0 0.36 1.27 1.29
37438 BRD-A09056319 ASC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
37977 BRD-A09056319 HT29 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.52
38292 BRD-A09056319 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.11
96074 BRD-A09056319 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).