CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01859
Pert ID:	BRD-K37355418
Compound Name:	efaproxiral
Targets:	HBA1\|HBB
MoA:	haemoglobin oxygen release stimulant
SMILES:	Cc1cc(C)cc(NC(=O)Cc2ccc(OC(C)(C)C(O)=O)cc2)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
123258	BRD-K37355418	A549	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123301	BRD-K37355418	HELA	1.11 uM	24 h	0.0	0.0	0.0	0.22	0.77	0.06
123330	BRD-K37355418	HT29	0.04 uM	24 h	0.0	0.0	0.0	0.26	0.91	0.24
123388	BRD-K37355418	MDAMB231	0.37 uM	24 h	0.0	0.0	0.0	-0.36	-1.22	1.24
123411	BRD-K37355418	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123446	BRD-K37355418	THP1	3.33 uM	24 h	-0.33	-1.38	1.08	0.29	1.04	0.56
123480	BRD-K37355418	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131521	BRD-K37355418	A375	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131572	BRD-K37355418	HA1E	2.22 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.39
131609	BRD-K37355418	HEK293	0.25 uM	24 h	0.0	0.0	0.0	0.33	1.17	0.93
131702	BRD-K37355418	HUVEC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131755	BRD-K37355418	JURKAT	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131810	BRD-K37355418	MCF10A	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131839	BRD-K37355418	MCF??7.00	2.22 uM	24 h	-0.22	-0.92	0.06	-0.28	-0.94	0.37

Summary