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CMap Candidate Details

Structure:
CMap ID: C01880
Pert ID: BRD-K82135108
Compound Name: elesclomol
Targets: HSPA1A
MoA: oxidative stress inducer
SMILES: CN(NC(=O)CC(=O)NN(C)C(=S)c1ccccc1)C(=S)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9521 BRD-K82135108 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9826 BRD-K82135108 H1299 10 uM 6 h -0.34 -1.43 1.43 0.0 0.0 0.0
10294 BRD-K82135108 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.06 0.75
10860 BRD-K82135108 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11588 BRD-K82135108 NCIH2073 10 uM 6 h -0.17 -0.7 0.0 0.22 0.77 0.05
12146 BRD-K82135108 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.13 0.99
12880 BRD-K82135108 SW480 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
13004 BRD-K82135108 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13688 BRD-K82135108 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
126390 BRD-K82135108 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126457 BRD-K82135108 HEK293 0.37 uM 24 h 0.28 1.18 0.39 -0.29 -0.97 0.44
126502 BRD-K82135108 HT29 3.33 uM 24 h 0.23 0.98 0.09 0.0 0.0 0.0
126562 BRD-K82135108 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134360 BRD-K82135108 A375 0.08 uM 24 h 0.0 0.0 0.0 -0.5 -1.7 15.65
134412 BRD-K82135108 HA1E 0.03 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
134441 BRD-K82135108 HELA 2.22 uM 24 h -0.26 -1.09 0.33 0.0 0.0 0.0
134524 BRD-K82135108 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134550 BRD-K82135108 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.61
134578 BRD-K82135108 MCF??7.00 0.08 uM 24 h -0.25 -1.06 0.25 0.19 0.66 0.01
134636 BRD-K82135108 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
134660 BRD-K82135108 YAPC 0.08 uM 24 h -0.24 -1.01 0.16 -0.22 -0.76 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).