CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01885
Pert ID:	BRD-K30466858
Compound Name:	ellagic-acid
Targets:	CA1\|CA12\|CA14\|CA2\|CA3\|CA4\|CA5A\|CA5B\|CA6\|CA7\|CA9\|CSNK2A1\|GSK3B\|PRKACA\|PRKCA\|PRKCB\|SQLE\|SYK
MoA:	glutathione transferase inhibitor; non-nucleoside reverse transcriptase inhibitor
SMILES:	Oc1cc2c3c(oc(=O)c4cc(O)c(O)c(oc2=O)c34)c1O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
90631	BRD-K30466858	HCT116	10 uM	24 h	0.0	0.0	0.0	-0.25	-0.84	0.18
90664	BRD-K30466858	MCF10A	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96438	BRD-K30466858	A375	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.42
96505	BRD-K30466858	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
98022	BRD-K30466858	MCF??7.00	0.37 uM	24 h	0.23	0.96	0.08	0.0	0.0	0.0
98069	BRD-K30466858	P1A82	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
98750	BRD-K30466858	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
98882	BRD-K30466858	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120009	BRD-K30466858	A549	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120038	BRD-K30466858	HA1E	0.125 uM	24 h	0.0	0.0	0.0	0.4	1.43	2.2
120076	BRD-K30466858	HELA	3.33 uM	3 h	0.0	0.0	0.0	0.0	0.0	0.0
120124	BRD-K30466858	HT29	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120226	BRD-K30466858	YAPC	1.11 uM	24 h	-0.2	-0.85	0.01	0.0	0.0	0.0

Summary