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CMap Candidate Details

Structure:
CMap ID: C01891
Pert ID: BRD-K54472332
Compound Name: elvitegravir
Targets:
MoA: HIV integrase inhibitor
SMILES: COc1cc2n(cc(C(O)=O)c(=O)c2cc1Cc1cccc(Cl)c1F)[C@H](CO)C(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
34381 BRD-K54472332 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34643 BRD-K54472332 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34910 BRD-K54472332 HEPG2 10 uM 6 h 0.27 1.12 0.27 0.0 0.0 0.0
35326 BRD-K54472332 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36836 BRD-K54472332 VCAP 10 uM 24 h -0.19 -0.78 0.0 0.36 1.29 1.45
96155 BRD-K54472332 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96296 BRD-K54472332 A375 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.47 15.35
96368 BRD-K54472332 PC3 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.99
121708 BRD-K54472332 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129607 BRD-K54472332 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129640 BRD-K54472332 HT29 0.74 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.43
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).