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CMap Candidate Details

Structure:
CMap ID: C01892
Pert ID: BRD-K86727142
Compound Name: embelin
Targets: XIAP
MoA: HCV inhibitor; XIAP inhibitor
SMILES: CCCCCCCCCCCC1C(=O)C(=O)CC(=O)C1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2933 BRD-K86727142 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3277 BRD-K86727142 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3556 BRD-K86727142 PC3 10 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
3883 BRD-K86727142 VCAP 10 uM 24 h 0.31 1.3 0.69 -0.33 -1.1 0.86
39510 BRD-K86727142 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40093 BRD-K86727142 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40358 BRD-K86727142 HT29 10 uM 6 h -0.17 -0.69 0.0 -0.29 -0.99 0.5
40653 BRD-K86727142 MCF??7.00 10 uM 6 h -0.18 -0.74 0.0 0.25 0.87 0.17
40901 BRD-K86727142 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41222 BRD-K86727142 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
41561 BRD-K86727142 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96971 BRD-K86727142 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).