CMap Candidate Details
Structure:
| CMap ID: | C01894 |
| Pert ID: | BRD-K47659338 |
| Compound Name: | EMD-386088 |
| Targets: | HTR6 |
| MoA: | serotonin receptor agonist |
| SMILES: | Cc1[nH]c2ccc(Cl)cc2c1C1=CCNCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 5210 | BRD-K47659338 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5337 | BRD-K47659338 | HA1E | 10 uM | 24 h | 0.25 | 1.06 | 0.18 | 0.0 | 0.0 | 0.0 |
| 5642 | BRD-K47659338 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6282 | BRD-K47659338 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6560 | BRD-K47659338 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37292 | BRD-K47659338 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.18 | 0.97 |
| 37675 | BRD-K47659338 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.01 | 0.58 |
| 37911 | BRD-K47659338 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38091 | BRD-K47659338 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.98 | 0.37 |
| 38236 | BRD-K47659338 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 38499 | BRD-K47659338 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.38 | 1.34 | 1.72 |
| 38736 | BRD-K47659338 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99581 | BRD-K47659338 | U2OS | 10 uM | 6 h | -0.22 | -0.91 | 0.05 | 0.0 | 0.0 | 0.0 |