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CMap Candidate Details

Structure:
CMap ID: C01896
Pert ID: BRD-K88759641
Compound Name: EMD-66684
Targets: AGTR1
MoA: angiotensin receptor antagonist
SMILES: CCCCc1nc2ccn(CC(=O)N(C)C)c(=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2936 BRD-K88759641 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
3282 BRD-K88759641 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3558 BRD-K88759641 PC3 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.65
3985 BRD-K88759641 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39360 BRD-K88759641 A549 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.25
39812 BRD-K88759641 ASC 10 uM 24 h -0.19 -0.8 0.0 0.0 0.0 0.0
40101 BRD-K88759641 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40366 BRD-K88759641 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40529 BRD-K88759641 MCF??7.00 10 uM 24 h 0.27 1.12 0.28 0.0 0.0 0.0
40909 BRD-K88759641 NEU 10 uM 24 h 0.0 0.0 0.0 0.22 0.8 0.08
41232 BRD-K88759641 NPC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.8
41572 BRD-K88759641 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97148 BRD-K88759641 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).