CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00190
Pert ID:	BRD-A03061970
Compound Name:	alizapride
Targets:	DRD2
MoA:	dopamine receptor antagonist
SMILES:	COc1cc2[nH]nnc2cc1C(=O)NCC1CCCN1CC=C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
122839	BRD-A03061970	A375	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122912	BRD-A03061970	HEK293	3.33 uM	24 h	0.27	1.13	0.29	-0.33	-1.1	0.87
122986	BRD-A03061970	HT29	10 uM	24 h	-0.29	-1.19	0.54	0.0	0.0	0.0
123037	BRD-A03061970	JURKAT	1.11 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.37
123066	BRD-A03061970	MCF10A	0.37 uM	24 h	0.18	0.76	0.0	0.24	0.86	0.15
123080	BRD-A03061970	MCF??7.00	0.04 uM	24 h	0.0	0.0	0.0	-0.44	-1.49	15.35
123127	BRD-A03061970	MDAMB231	0.37 uM	24 h	0.26	1.09	0.23	0.18	0.62	0.0
123199	BRD-A03061970	THP1	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123220	BRD-A03061970	YAPC	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131255	BRD-A03061970	A549	0.25 uM	24 h	-0.24	-0.98	0.12	-0.25	-0.85	0.2
131289	BRD-A03061970	HA1E	2.22 uM	24 h	0.28	1.18	0.39	-0.31	-1.06	0.72
131313	BRD-A03061970	HELA	0.25 uM	24 h	0.0	0.0	0.0	-0.22	-0.72	0.04
131471	BRD-A03061970	PC3	0.03 uM	24 h	0.0	0.0	0.0	-0.23	-0.79	0.11

Summary