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CMap Candidate Details

Structure:
CMap ID: C01904
Pert ID: BRD-K57545991
Compound Name: enalapril
Targets: ACE
MoA: angiotensin converting enzyme inhibitor
SMILES: CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4447 BRD-K57545991 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5094 BRD-K57545991 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37701 BRD-K57545991 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38522 BRD-K57545991 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38751 BRD-K57545991 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
91270 BRD-K57545991 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99694 BRD-K57545991 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119883 BRD-K57545991 A549 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119921 BRD-K57545991 PC3 0.01 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
123796 BRD-K57545991 A375 10 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
123872 BRD-K57545991 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123901 BRD-K57545991 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123944 BRD-K57545991 HELA 10 uM 24 h 0.27 1.13 0.28 0.0 0.0 0.0
124002 BRD-K57545991 JURKAT 0.04 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
124055 BRD-K57545991 MCF10A 10 uM 24 h -0.27 -1.13 0.41 0.0 0.0 0.0
124096 BRD-K57545991 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124125 BRD-K57545991 MDAMB231 10 uM 24 h 0.28 1.19 0.41 0.0 0.0 0.0
124184 BRD-K57545991 THP1 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
124236 BRD-K57545991 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132228 BRD-K57545991 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).