CMap Candidate Details
Structure:
| CMap ID: | C01917 |
| Pert ID: | BRD-K78113049 |
| Compound Name: | enoxacin |
| Targets: | TOP2A |
| MoA: | topoisomerase inhibitor |
| SMILES: | CCn1cc(C(O)=O)c(=O)c2cc(F)c(nc12)N1CCNCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 52196 | BRD-K78113049 | MCF??7.00 | 10 uM | 6 h | -0.24 | -0.99 | 0.14 | 0.0 | 0.0 | 0.0 |
| 91272 | BRD-K78113049 | HUH7 | 10 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99505 | BRD-K78113049 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127051 | BRD-K78113049 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.69 | 0.03 |
| 127114 | BRD-K78113049 | HELA | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127189 | BRD-K78113049 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127253 | BRD-K78113049 | PC3 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.83 | 0.12 |
| 127325 | BRD-K78113049 | YAPC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135020 | BRD-K78113049 | A375 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.01 | 0.44 |
| 135057 | BRD-K78113049 | A549 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135114 | BRD-K78113049 | HEK293 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.34 |
| 135151 | BRD-K78113049 | HT29 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.02 | 0.46 |
| 135184 | BRD-K78113049 | JURKAT | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.26 | 1.35 |
| 135282 | BRD-K78113049 | MDAMB231 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135314 | BRD-K78113049 | THP1 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.02 | 0.48 |