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CMap Candidate Details

Structure:
CMap ID: C01920
Pert ID: BRD-K35007173
Compound Name: enprofylline
Targets: ADORA1|ADORA2A|ADORA2B|ADORA3|PDE4A|PDE4B
MoA: phosphodiesterase inhibitor
SMILES: CCCn1c2nc[nH]c2c(=O)[nH]c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96775 BRD-K35007173 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121804 BRD-K35007173 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121873 BRD-K35007173 YAPC 1.11 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.31
129767 BRD-K35007173 A375 2.22 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
129802 BRD-K35007173 HA1E 0.03 uM 24 h -0.25 -1.04 0.2 0.0 0.0 0.0
129844 BRD-K35007173 HEK293 0.01 uM 24 h 0.24 1.01 0.11 -0.31 -1.03 0.63
129879 BRD-K35007173 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129925 BRD-K35007173 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129970 BRD-K35007173 MCF10A 0.25 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
130008 BRD-K35007173 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130055 BRD-K35007173 MDAMB231 0.74 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
130126 BRD-K35007173 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).