CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01923
Pert ID:	BRD-K08206212
Compound Name:	entecavir
Targets:
MoA:	DNA replication inhibitor; nucleoside reverse transcriptase inhibitor
SMILES:	Nc1nc(=O)c2ncn([C@H]3C[C@H](O)[C@@H](CO)C3=C)c2[nH]1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
33774	BRD-K08206212	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
34040	BRD-K08206212	ASC	10 uM	24 h	-0.24	-1.02	0.17	0.0	0.0	0.0
34554	BRD-K08206212	HCC515	10 uM	6 h	0.0	0.0	0.0	-0.33	-1.1	0.86
34823	BRD-K08206212	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35725	BRD-K08206212	NPC	10 uM	24 h	0.0	0.0	0.0	-0.36	-1.2	1.17
36198	BRD-K08206212	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36491	BRD-K08206212	SKB	10 uM	24 h	-0.17	-0.7	0.0	-0.32	-1.09	0.81
36771	BRD-K08206212	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96509	BRD-K08206212	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121213	BRD-K08206212	HA1E	10 uM	24 h	-0.24	-1.02	0.18	0.0	0.0	0.0
121247	BRD-K08206212	HELA	10 uM	24 h	0.0	0.0	0.0	0.48	1.69	2.51
129241	BRD-K08206212	A375	2.22 uM	24 h	0.0	0.0	0.0	0.26	0.93	0.28
129288	BRD-K08206212	HT29	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129324	BRD-K08206212	MCF??7.00	2.22 uM	24 h	0.0	0.0	0.0	0.2	0.72	0.02
129361	BRD-K08206212	YAPC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary