Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C01944
Pert ID: BRD-K02314383
Compound Name: epitiostanol
Targets: AR
MoA: androgen receptor agonist
SMILES: C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@@H]5S[C@@H]5C[C@]34C)[C@@H]1CC[C@@H]2O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122835 BRD-K02314383 A375 10 uM 24 h -0.36 -1.49 1.43 0.0 0.0 0.0
122863 BRD-K02314383 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122902 BRD-K02314383 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
122944 BRD-K02314383 HELA 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
122978 BRD-K02314383 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.26
123027 BRD-K02314383 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123065 BRD-K02314383 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123076 BRD-K02314383 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123117 BRD-K02314383 MDAMB231 0.125 uM 24 h 0.29 1.2 0.42 0.0 0.0 0.0
123189 BRD-K02314383 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131250 BRD-K02314383 A549 0.74 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
131365 BRD-K02314383 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
131466 BRD-K02314383 PC3 0.74 uM 24 h -0.26 -1.1 0.35 0.0 0.0 0.0
131502 BRD-K02314383 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).