CMap Candidate Details
Structure:
| CMap ID: | C01945 |
| Pert ID: | BRD-K19761926 |
| Compound Name: | eplerenone |
| Targets: | NR3C2 |
| MoA: | cytochrome P450 inhibitor |
| SMILES: | COC(=O)[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@@]23O[C@@H]2C[C@@]2(C)[C@@H](CC[C@@]22CCC(=O)O2)[C@H]13 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90899 | BRD-K19761926 | MCF10A | 3.33 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121437 | BRD-K19761926 | HT29 | 3.33 uM | 24 h | 0.22 | 0.93 | 0.05 | 0.29 | 1.04 | 0.53 |
| 121459 | BRD-K19761926 | MCF??7.00 | 10 uM | 24 h | 0.23 | 0.96 | 0.07 | 0.0 | 0.0 | 0.0 |
| 121509 | BRD-K19761926 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.86 | 0.21 |
| 129403 | BRD-K19761926 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129433 | BRD-K19761926 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129465 | BRD-K19761926 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.05 | 0.69 |
| 129553 | BRD-K19761926 | PC3 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |