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CMap Candidate Details

Structure:
CMap ID: C01948
Pert ID: BRD-K71823332
Compound Name: epothilone-a
Targets:
MoA: microtubule stabilizing agent
SMILES: C[C@H]1CCC[C@H]2O[C@H]2C[C@H](OC(=O)C[C@H](O)C(C)(C)C(=O)[C@H](C)[C@H]1O)C(\C)=C\c1csc(C)n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29933 BRD-K71823332 A375 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
30105 BRD-K71823332 A549 10 uM 24 h -0.19 -0.78 0.0 -0.3 -1.02 0.62
30538 BRD-K71823332 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30830 BRD-K71823332 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31121 BRD-K71823332 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31434 BRD-K71823332 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31572 BRD-K71823332 HT29 10 uM 6 h -0.25 -1.06 0.25 -0.26 -0.86 0.22
31918 BRD-K71823332 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.33 1.15 0.9
32513 BRD-K71823332 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32822 BRD-K71823332 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33121 BRD-K71823332 SKB 10 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.97
33501 BRD-K71823332 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90820 BRD-K71823332 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).