CMap Candidate Details
Structure:
| CMap ID: | C01962 |
| Pert ID: | BRD-K70446295 |
| Compound Name: | EPZ015666 |
| Targets: | PRMT5 |
| MoA: | protein arginine N-methyltransferase inhibitor |
| SMILES: | O[C@@H](CNC(=O)c1cc(NC2COC2)ncn1)CN1CCc2ccccc2C1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95501 | BRD-K70446295 | A549 | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.72 | 0.04 |
| 95569 | BRD-K70446295 | MCF??7.00 | 10 uM | 48 h | 0.23 | 0.98 | 0.09 | 0.0 | 0.0 | 0.0 |
| 95659 | BRD-K70446295 | U2OS | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.2 | 0.7 | 0.02 |
| 96745 | BRD-K70446295 | A375 | 10 uM | 24 h | 0.22 | 0.93 | 0.05 | 0.0 | 0.0 | 0.0 |
| 96794 | BRD-K70446295 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |