CMap Candidate Details
Structure:
| CMap ID: | C01965 |
| Pert ID: | BRD-K54847683 |
| Compound Name: | equol |
| Targets: | ESR1|ESR2 |
| MoA: | estrogen receptor agonist |
| SMILES: | Oc1ccc(cc1)[C@H]1COc2cc(O)ccc2C1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 124277 | BRD-K54847683 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124323 | BRD-K54847683 | HEK293 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.36 | 1.28 | 1.36 |
| 124360 | BRD-K54847683 | HELA | 10 uM | 24 h | 0.34 | 1.41 | 1.03 | -0.3 | -1.01 | 0.56 |
| 124428 | BRD-K54847683 | JURKAT | 10 uM | 24 h | -0.23 | -0.96 | 0.1 | 0.0 | 0.0 | 0.0 |
| 124454 | BRD-K54847683 | MCF10A | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124494 | BRD-K54847683 | MDAMB231 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124523 | BRD-K54847683 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.91 | 0.31 |
| 124553 | BRD-K54847683 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132365 | BRD-K54847683 | A549 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132394 | BRD-K54847683 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132468 | BRD-K54847683 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.2 | 1.13 |
| 132529 | BRD-K54847683 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132616 | BRD-K54847683 | THP1 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.89 | 0.27 |