CMap Candidate Details
Structure:
| CMap ID: | C01966 |
| Pert ID: | BRD-K11927976 |
| Compound Name: | ER-27319 |
| Targets: | SYK |
| MoA: | mediator release inhibitor; SYK inhibitor |
| SMILES: | Cc1ccc2c(c1C)n(CCCN)c1ccccc1c2=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1740 | BRD-K11927976 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.23 | 1.21 |
| 2081 | BRD-K11927976 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.44 | 1.57 | 2.34 |
| 2375 | BRD-K11927976 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.14 | 0.87 |
| 41726 | BRD-K11927976 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42060 | BRD-K11927976 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42298 | BRD-K11927976 | ASC | 10 uM | 24 h | -0.18 | -0.75 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42631 | BRD-K11927976 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42934 | BRD-K11927976 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.18 | 0.98 |
| 43294 | BRD-K11927976 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43794 | BRD-K11927976 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44071 | BRD-K11927976 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.93 | 0.26 |
| 100087 | BRD-K11927976 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.86 | 0.16 |