CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01970
Pert ID:	BRD-K84163249
Compound Name:	ercalcitriol
Targets:	VDR
MoA:	vitamin D receptor agonist
SMILES:	C[C@H](\C=C\[C@H](C)C(C)(C)O)[C@H]1CC[C@@H]2[C@]1(C)CCC\C2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95303	BRD-K84163249	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
95426	BRD-K84163249	U2OS	10 uM	48 h	0.0	0.0	0.0	-0.29	-0.97	0.45
125966	BRD-K84163249	A375	10 uM	24 h	0.0	0.0	0.0	0.32	1.15	0.89
126033	BRD-K84163249	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126090	BRD-K84163249	HUVEC	10 uM	24 h	0.0	0.0	0.0	-0.22	-0.76	0.07
126138	BRD-K84163249	JURKAT	0.125 uM	24 h	-0.25	-1.06	0.24	-0.33	-1.12	0.93
126191	BRD-K84163249	MCF10A	3.33 uM	24 h	-0.22	-0.92	0.06	0.0	0.0	0.0
126309	BRD-K84163249	THP1	10 uM	24 h	0.22	0.92	0.04	0.24	0.84	0.12
134071	BRD-K84163249	HA1E	0.03 uM	24 h	0.0	0.0	0.0	0.25	0.9	0.22
134113	BRD-K84163249	HEK293	0.25 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.49
134186	BRD-K84163249	HT29	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134233	BRD-K84163249	MCF??7.00	2.22 uM	24 h	0.19	0.8	0.0	0.27	0.96	0.33
134266	BRD-K84163249	MDAMB231	2.22 uM	24 h	-0.19	-0.77	0.0	0.25	0.88	0.18
134289	BRD-K84163249	PC3	0.01 uM	24 h	0.0	0.0	0.0	0.31	1.08	0.66
134320	BRD-K84163249	YAPC	0.03 uM	24 h	0.0	0.0	0.0	-0.27	-0.92	0.33

Summary